The Antibacterial Activity Of Leaf Extracts Of Ocimum Gratissimum And Sida Acuta

ABSTRACT

The antibacterial activities of ethanolic and aqueous extracts of Sida acuta and Ocimum gratissimum on Escherichia coli, Staphylococcus aureus, Streptococcus faecalis and Pseudomonas aeruginosa were detennined using disc diffusion assays. All the extracts exhibited moderate to high level of inhibition against the four microorganisms. The antibacterial activities were measured by the diameter zone of inhibition, in which ethanolic extracts or Sida acuta exhibit the highest yield which is 18mm and the lowest yield in aqueous (cold) is 10mm. Also on Ocimum gratissimum ethanol extract is 15mm while the lowest on aqueous (cold) extract 7mm. The minimum inhibitory concentration (MIC) is 0.125mg/ml on both plant extracts using the ethanol extracts by Staphylococcus aureus. The antibacterial effect of aqueous (cold) and ethanolic extracts of Sida acuta I ' and Ocimum gratissimum were positive on both the four microorganism and the minimum inhibitory concentration (MIC) were also positive on gram positive and gram negative organisms. This research is discussed in relation to the acceptable herbal medicines as a means of disease control.