Antimicrobial Susceptibility Pattern S Of Bacterial Isolates From Patients With Urinary Catheter At Federal Medical Center, Umuahia:- Godwin, Chukwudi T

ABSTRACT

The antimicrobial susceptibility pattern of bacterial isolates from patients with urinary catheter at Federal Medical Center, Umuahia, Ahia state, of Nigeria was studied. A total of33 catheter urine samples were collected from patients admitted at Federal Medical Center, Umuahia. Samples collected were cultured on MacConkey agar and Cystein Lactose Electrolyte Deficient (CLED) agar using the streaking method. Pure colonies of isolate were biochemically characterized. identified and the antibiotic susceptibility test performed using Muller Hinton agar. Out of the 33 samples analyzed, 21 (63.64%) produced significant growth with 23 microbial isolates. The bacterial isolates included E. coil 8 (34.70%), followed by Pseudomnas aeruginosa 5 (21.74%), Klebsiella sp 4(17.39%), Staphylococcus aureus 3 (13.04%) and Proteus mirabilis 3 (13.04%). The isolates showed high resistance to commonly used antibiotics such as arnpicillin (100%), tetracycline (95.65%), augumentin (91.30%), cotrimaxole (91.30%), gentamycin (82.61%) and nalixidic acid (82.61%). Intermediate level of resistance was found against ofloxacin (69.57%) and perfloxacin (60.87%). Only nitrofurantoin and ciprofloxacin (56.52% and 43.48% sensitivity respectively) appeared most effective. Therefore, treatment of patients with catheter associated urinary tract infection in this institution should be guided by the result of susceptibility test of isolates and based on doctor's prescription so as to reduce the incidence of multiple-resistance.